A common heterocyclic compound, 152628-03-0, name is 4-Methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylic acid, molecular formula is C12H14N2O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. 152628-03-0.
Methyl-6-carboxybenzimidazole 5. 00 kg, methylene chloride 15. 00 kg A solution of 3. 28 kg of thionyl chloride was added dropwise under stirring at 25 C with stirring. Reaction 1 hour, spare
The synthetic route of 4-Methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylic acid has been constantly updated, and we look forward to future research findings.
Reference:
Patent; WEITE(Hunan)Pharmaceutical co.,ltd,; he, liang; Luo, Hui; Mo, Wei; (9 pag.)CN105237457; (2016); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem